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Article

Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci.

British journal of cancer - 26 Jan 2004

Brown W M, Lange E M, Chen H, Zheng S L, Chang B, Wiley K E, Isaacs S D, Walsh P C, Isaacs W B, Xu J, Cooney K A

Abstract excerpt

African American men have the highest incidence of prostate cancer in the world. Despite this statistic, linkage studies designed to localise prostate cancer susceptibility alleles have included primarily men of Caucasian descent. In this report, we performed a linkage analysis using 33 African American prostate cancer families from two independent research groups. In total, 126 individuals (including 89 men with...

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PMID: 14735201
DOI: 10.1038/sj.bjc.6601417
PMCID: PMC2410149

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Hereditary prostate cancer in African American families: linkage analysis using markers that map to five candidate susceptibility loci.PMID 14735201Read ↗

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Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans.Semantic proximity Read ↗

Genome linkage screen for prostate cancer susceptibility loci: results from the Mayo Clinic Familial Prostate Cancer Study.Semantic proximity Read ↗

Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX.Semantic proximity Read ↗

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In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer.Semantic proximity Read ↗

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