Article

Epigenetic analysis identifies factors driving racial disparity in prostate cancer

2018-06-20

Abstract excerpt

Prostate cancer (PCa) is the second most leading cause of death in men worldwide. African American men (AA) represent more aggressive form of PCa as compared to Caucasian (CA) counterparts. Evidence suggests that genetic and other biological factors could account for the observed racial disparity. We analyzed the cancer genome atlas (TCGA) dataset (2015) for existing epigenetic variation in AA and CA prostate canc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d5f133d-0af5-598d-b1ee-0da5bccb3038
DOI: 10.1101/352138

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Epigenetic analysis identifies factors driving racial disparity in prostate cancerDOI 10.1101/352138Read

Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patientsSemantic proximity Read

Racial disparities in prostate cancer: a molecular perspective.Semantic proximity Read

Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancerSemantic proximity Read

Biological determinants of health disparities in prostate cancerSemantic proximity Read

Epigenome‐wide association study of prostate cancer in African American men identified differentially methylated genesSemantic proximity Read

Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian menSemantic proximity Read

Molecular Discriminators of Racial Disparities in Prostate Cancer.Semantic proximity Read

Racial Disparity in Utilizing Genetic Testing for Personalized Care of Prostate CancerSemantic proximity Read

Alterations in the Epigenetic Machinery Associated with Prostate Cancer Health DisparitiesSemantic proximity Read

Alterations in the Epigenetic Machinery Associated With Prostate Cancer Health DisparitiesSemantic proximity Read

Race and prostate cancer: genomic landscape.Semantic proximity Read

The Impact of African Ancestry on Prostate Cancer Disparities in the Era of Precision MedicineSemantic proximity Read