Chats and Spats of Autophagy and Innate Immune Systems

Abstract excerpt

• Autophagy plays a critical role in maintaining innate immune homeostasis. • Many stimuli that trigger innate immune signaling, also activate autophagy. • Autophagy degrades key components of innate immune pathways to suppress proinflammatory response. • Therapeutic targeting of autophagy-innate immunity crosstalk holds significant promise for improving human health. The innate immune system and autophagy are...