Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Continue to focus clinical decision-making on the antigen recognition domain for the present.

Human immunology - 1 Jan 2019

Hurley Carolyn Katovich, Ng Jennifer

Abstract excerpt

Next generation DNA sequencing has facilitated the routine characterization of complete HLA gene sequences. These data complement structural and functional studies of HLA elements encoded outside of the exons specifying the antigen recognition domain. This commentary is focused on evaluating whether the interpretation of HLA clinical typing results should expand the region of the HLA gene considered in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Antigens
Share to Clinical Decision-Making

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to HLA Antigens

Share to Protein Binding

Share to Protein Interaction Domains and Motifs

Source

Identifiers

PMID: 29684413
DOI: 10.1016/j.humimm.2018.04.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Continue to focus clinical decision-making on the antigen recognition domain for the present.PMID 29684413Read ↗

The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside.Semantic proximity Read ↗

HLA variation and disease.Semantic proximity Read ↗

On the future of HLA.Semantic proximity Read ↗

HLA-G Genotype/Expression/Disease Association Studies: Success, Hurdles, and Perspectives.Semantic proximity Read ↗

A new categorization of HLA DR alleles on a functional basis.Semantic proximity Read ↗

HLA class I polymorphism: structure and function and still questions.Semantic proximity Read ↗

The impact of amino acid variability on alloreactivity defines a functional distance predictive of permissive HLA-DPB1 mismatches in hematopoietic stem cell transplantation.Semantic proximity Read ↗

Microsatellites in the HLA region: HLA prediction and strategies for bone marrow donor registries.Semantic proximity Read ↗

HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypesSemantic proximity Read ↗

Identifying genes that cause disease: HLA-B27, the paradigm, the promise, the perplexity.Semantic proximity Read ↗

HLA and disease: guilt by association.Semantic proximity Read ↗

Limited HLA sequence variation outside of antigen recognition domain exons of 360 10 of 10 matched unrelated hematopoietic stem cell transplant donor‐recipient pairsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.