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Article

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy

11 Apr 2018

Abstract excerpt

The prevalence of respiratory allergy in children is increasing. Epigenetic DNA methylation changes are plausible underlying molecular mechanisms. Saliva samples collected in substudies of two longitudinal birth cohorts in Belgium (FLEHS1 & FLEHS2) were used to discover and confirm DNA methylation signatures that can differentiate individuals with respiratory allergy from healthy subjects. Genome-wide analysis...

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PMID: 29682088
DOI: 10.1186/s13148-018-0484-1

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