Article
Tagging SNPs in the HOTAIR gene are associated with bladder cancer risk in a Chinese population.
Gene - 20 Jul 2018
Wang Xiang, Wang Wenying, Zhang Qiang, Gu Damin, Zhang Ke, Ge Yuqiu, Chu Haiyan, Du Mulong, Xu Bin, Wang Meilin, Lv Xu, Zhang Zhengdong, Yuan Lin, Gong Weida
Abstract excerpt
BACKGROUND: The HOX transcript antisense intergenic RNA (HOTAIR) is a well-known long noncoding RNA (lncRNA) that plays a critical role in biological processes in most cancers. However, the function of HOTAIR in bladder cancer remains largely unknown. In this study, we hypothesize that tag single nucleotide polymorphisms (tagSNPs) in HOTAIR are associated with bladder cancer (BCa) risk. METHODS: We performed a...
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