Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic testing for hereditary prostate cancer: Current status and limitations.

Cancer - 1 Aug 2018

Zhen Jun Tu, Syed Jamil, Nguyen Kevin Anh, Leapman Michael S, Agarwal Neeraj, Brierley Karina, Llor Xavier, Hofstatter Erin, Shuch Brian

Abstract excerpt

A significant proportion of prostate cancer diagnoses may be associated with a strong hereditary component. Men who have multiple single-gene polymorphisms and a family history of prostate cancer have a significantly greater risk of developing prostate cancer. Numerous single-gene alterations have been confirmed to increase the risk of prostate cancer. These include breast cancer genes 1 and 2 (BRCA1 and BRCA2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Germ-Line Mutation

Share to Neoplasm Proteins

Share to Polymorphism, Single Nucleotide

Share to Prostatic Neoplasms

Source

Identifiers

PMID: 29669169
DOI: 10.1002/cncr.31316

Genes

BRCA1
ATM
BRCA2
BRIP1
CHEK2
HOXB13
MLH1
MSH2
MSH6
NBN
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic testing for hereditary prostate cancer: Current status and limitations.PMID 29669169Read ↗

Germline genetics of prostate cancer.Semantic proximity Read ↗

Genetic testing in prostate cancer management: Considerations informing primary care.Semantic proximity Read ↗

Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testingSemantic proximity Read ↗

Recent Insights on Genetic Testing in Primary Prostate Cancer.Semantic proximity Read ↗

Hereditary prostate cancer - Primetime for genetic testing?Semantic proximity Read ↗

Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease ManagementSemantic proximity Read ↗

The role of genetic testing in prostate cancer screening, diagnosis, and treatment.Semantic proximity Read ↗

Diagnosing hereditary cancer predisposition in men with prostate cancer.Semantic proximity Read ↗

Germline genetic variants in men with prostate cancer and one or more additional cancers.Semantic proximity Read ↗

Prostate cancer and genetic contributions.Semantic proximity Read ↗

Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications.Semantic proximity Read ↗

Hereditary Prostate Cancer: Genes Related, Target Therapy and PreventionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.