Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment and characterization of a C57BL/6 mouse model of bone metastasis of breast cancer.

Journal of bone and mineral metabolism - 1 Mar 2019

Hiraga Toru, Ninomiya Tadashi

Abstract excerpt

Bone is one of the most common sites of metastasis in patients with advanced breast cancer; however, the mechanisms of bone metastasis remain to be fully elucidated. Animal models are essential research tools for investigating the mechanisms of diseases and drug actions. To date, there have only been a few reports in which C57BL/6 mice were used for the study of bone metastases of breast cancer. In the current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Neoplasms
Share to Disease Models, Animal
Share to Mammary Neoplasms, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Neoplastic Stem Cells

Share to Phenotype

Source

Identifiers

PMID: 29667006
DOI: 10.1007/s00774-018-0927-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment and characterization of a C57BL/6 mouse model of bone metastasis of breast cancer.PMID 29667006Read ↗

Mechanisms of bone metastases of breast cancerSemantic proximity Read ↗

Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature.Semantic proximity Read ↗

A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone.Semantic proximity Read ↗

Exploiting bone niches: progression of disseminated tumor cells to metastasisSemantic proximity Read ↗

Bone marrow B cell collapse promotes bone metastasis in breast cancerSemantic proximity Read ↗

The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humansSemantic proximity Read ↗

Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodelingSemantic proximity Read ↗

A Novel Model of Estrogen Receptor-Positive Breast Cancer Bone Metastasis with Antiestrogen ResponsivenessSemantic proximity Read ↗

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumorsSemantic proximity Read ↗

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors.Semantic proximity Read ↗

The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formationSemantic proximity Read ↗

Both human and mouse mesenchymal stem cells promote breast cancer metastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.