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Article

A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.

Journal of clinical laboratory analysis - 1 Sept 2018

Alavian Seyed Ehsan, Sharafi Heidar, Shirmast Paniz, Alavian Seyed Moayed, Behnava Bita, Pouryasin Mohammad, Keshvari Maryam, Pouryasin Ali

Abstract excerpt

BACKGROUND: Inosine triphosphate pyrophosphatase (ITPA) gene single nucleotide polymorphisms (SNPs), rs1127354 and rs7270101, may cause a functional impairment in ITPase enzyme, resulting anemia protection in patients with chronic hepatitis C virus (HCV) infection undergoing ribavirin (RBV)-dependent regimens. The main purpose of this study was to provide and validate a simple, rapid, and inexpensive polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antiviral Agents
Share to Cohort Studies
Share to Genotyping Techniques
Share to Hepatitis C, Chronic
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Share to Polymorphism, Restriction Fragment Length
Share to Pyrophosphatases
Share to Ribavirin

Source

Open in PubMed Open full text

Identifiers

PMID: 29660762
DOI: 10.1002/jcla.22440
PMCID: PMC6816863

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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A facile PCR-RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms.PMID 29660762Read ↗

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