Article
A Simple PCR-RFLP Method for Genotyping of IFNL4 rs368234815 Polymorphism in Patients With Chronic Hepatitis C.
Laboratory medicine - 1 Feb 2017
Pouryasin Mohammad, Sharafi Heidar, Behnava Bita, Alavian Seyed Moayed, Keshvari Maryam, Pouryasin Ali
Abstract excerpt
BACKGROUND: The IFNL4 rs368234815 polymorphism plays a prominent role in spontaneous and treatment-induced clearance of hepatitis C virus (HCV) infection. This study aimed to develop a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method for assessment of rs368234815 polymorphism. METHODS: We genotyped the rs368234815 polymorphism in 87 patients with chronic HCV by PCR sequencing...
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