Article
High resolution allele genotyping and haplotype frequencies for NGS based HLA 11 loci of 5266 Hong Kong Chinese bone marrow donors.
Human immunology - 1 Jan 2000
Kwok Janette, Tang W H, Chu W K, Chan Y S, Liu Zhongyi, Yang Wanling, Ip Patrick, Ma Wen, Lee C K, Middleton Derek
Abstract excerpt
Next-generation sequencing (NGS) at the HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1, and -DPB1 loci was performed on 5,266 southern Chinese unrelated donors of the Hong Kong Bone Marrow Donor Registry. High-resolution HLA genotypes defined by full sequencing of class I loci and extended coverage of class II loci were attained to determine allele frequencies and estimate haplotype frequencies. This study...
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