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Article

A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.

The Journal of pathology - 1 Jul 2018

Simard Marie-Lune, Mourier Arnaud, Greaves Laura C, Taylor Robert W, Stewart James B

Abstract excerpt

Defects in the respiratory chain, interfering with energy production in the cell, are major underlying causes of mitochondrial diseases. In spite of this, the surprising variety of clinical symptoms, disparity between ages of onset, as well as the involvement of mitochondrial impairment in ageing and age-related diseases continue to challenge our understanding of the pathogenic processes. This complexity can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29660116
DOI: 10.1002/path.5084
PMCID: PMC6032845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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