Article
Effects of titanium surface roughness on the mediation of osteogenesis via modulating the immune response of macrophages.
Biomedical materials (Bristol, England) - 15 May 2018
Li Xuezhong, Huang Qianli, Elkhooly Tarek A, Liu Yong, Wu Hong, Feng Qingling, Liu Ling, Fang Yu, Zhu Weihong, Hu Tianrui
Abstract excerpt
Osteoblastic lineage cells are commonly used to evaluate the in vitro osteogenic ability of bone biomaterials. However, contradictory results obtained from in vivo and in vitro studies are not uncommon. With the increasing understanding of osteoimmunology, the immune response has been recognized as playing an important role in bone regeneration. In this study, we examined the effect of submicron-scaled titanium...
Topics
- Alkaline Phosphatase
- Animals
- Biocompatible Materials
- Bone Regeneration
- Bone and Bones
- Cell Differentiation
- Cell Lineage
- Cell Proliferation
- Collagen
- Culture Media, Conditioned