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Article

Improving classification of melanocytic nevi: Association of BRAF V600E expression with distinct histomorphologic features.

Journal of the American Academy of Dermatology - 1 Aug 2018

Kiuru Maija, Tartar Danielle M, Qi Lihong, Chen Danyang, Yu Lan, Konia Thomas, McPherson John D, Murphy William J, Fung Maxwell A

Abstract excerpt

BACKGROUND: A subset of melanomas carrying a B-Raf proto-oncogene, serine/threonine kinase gene (BRAF) V600E mutation, which is the most common targetable mutation in melanoma, arise in association with a melanocytic nevus that is also harboring a BRAF V600E mutation. The detailed histomorphologic characteristics of nevi positive for BRAF V600E have not been systematically documented. OBJECTIVE: To identify...

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Identifiers

PMID: 29653212
DOI: 10.1016/j.jaad.2018.03.052
PMCID: PMC6090558

Genes

BRAF

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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