Article
Reflectance confocal microscopy features of BRAF V600E mutated thin melanomas detected by immunohistochemistry.
PloS one - 1 Jan 2017
Urvanegia Ana Claudia, Tavoloni Braga Juliana Casagrande, Shitara Danielle, Fregnani Jose Humberto, Neves Jose Ivanildo, Pinto Clovis Antonio, Marghoob Ashfaq A, Duprat Joao Pedreira, Rezze Gisele Gargantini
Abstract excerpt
The classification of melanoma into four histological subtypes has been questioned regarding its clinical validity in providing relevant information for treatment for metastatic tumors. Specific genetic alterations are associated with particular clinical and histopathological features, suggesting that these could be helpful in refining existing melanoma classification schemes. We analyzed BRAF V600E mutated...
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