Article
Generation of autochthonous mouse models of clear cell renal cell carcinoma: mouse models of renal cell carcinoma.
Experimental & molecular medicine - 13 Apr 2018
Hou Weibin, Ji Zhigang
Abstract excerpt
Renal cell carcinoma (RCC) is one of the 10 most common cancers worldwide, and to date, a strong systemic therapy has not been developed to treat RCC, even with the remarkable modern advances in molecular medicine mostly due to our incomplete understanding of its tumorigenesis. There is a dire unmet need to understand the etiology and progression of RCC, especially the most common subtype, clear cell RCC (ccRCC),...
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