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Article

Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma.

European urology - 1 Apr 2011

Karam Jose A, Zhang Xiu-Ying, Tamboli Pheroze, Margulis Vitaly, Wang Hua, Abel E Jason, Culp Stephen H, Wood Christopher G

Abstract excerpt

BACKGROUND: Animal models are instrumental in understanding disease pathophysiology and mechanisms of therapy action and resistance in vivo. OBJECTIVE: To establish and characterize a panel of mouse models of renal cell carcinoma (RCC) derived from patients undergoing radical nephrectomy. DESIGN, SETTING, AND PARTICIPANTS: In vivo and in vitro animal experiments. MEASUREMENTS: Tumor tissues obtained during...

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Identifiers

PMID: 21167632
DOI: 10.1016/j.eururo.2010.11.043

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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