Article
Causal Pathways from Blood Pressure to Larger Qrs Amplitudes a Mendelian Randomization Study.
Scientific reports - 11 Apr 2018
Van Der Ende M Yldau, Hendriks Tom, Van Veldhuisen Dirk J, Snieder Harold, Verweij Niek, Van Der Harst Pim
Abstract excerpt
Abnormal QRS duration and amplitudes on the electrocardiogram are indicative of cardiac pathology and are associated with adverse outcomes. The causal nature of these associations remains uncertain and could be due to QRS abnormalities being a symptom of cardiac damage rather than a factor on the causal pathway. By performing Mendelian randomization (MR) analyses using summary statistics of genome wide...
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