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A retrospective investigation of HLA-B*5801 in hyperuricemia patients in a Han population of China

10 Apr 2018

Abstract excerpt

BACKGROUND: Hyperuricemia and gout have become increasingly prevalent in China. Allopurinol is an effective urate-lowering therapy, but it has severe side effects. HLA-B*5801 is highly associated with the allopurinol-induced toxic epidermal necrolysis and Stevens-Johnson syndrome. PATIENTS AND METHODS: In this retrospective report, we had genotyped HLA-B*5801 in 253 cases of hyperuricemia and gout patients in a...

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PMID: 29642234
DOI: 10.1097/fpc.0000000000000334

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