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Article

Tissue Distribution and Gender-Specific Protein Expression of Cytochrome P450 in five Mouse Genotypes with a Background of FVB.

Pharmaceutical research - 10 Apr 2018

Chen Jiamei M, Zhang Qisong S, Li Xiaoyan Y, Gong Xia, Ruan Yanjiao J, Zeng Sijing J, Lu Linlin L, Qi Xiaoxiao X, Wang Ying, Hu Ming, Zhu Lijun J, Liu Zhongqiu Q

Abstract excerpt

PURPOSE: To systematically investigate tissue distribution and gender-specific protein expression of Cytochrome P450 (Cyps) in five mouse genotypes with a background of Friend virus B (FVB). METHODS: The Cyps were extracted from the tissue S9 fractions of the main metabolic organs and then absolutely quantified by applying the UHPLC-MS/MS method. RESULTS: The liver had the highest expression of Cyps, followed by...

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PMID: 29637468
DOI: 10.1007/s11095-018-2389-2

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