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Article

Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture.

Scientific reports - 10 Apr 2018

Awandare Gordon A, Nyarko Prince B, Aniweh Yaw, Ayivor-Djanie Reuben, Stoute José A

Abstract excerpt

The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neuraminidase-treated erythrocytes. Following an observation of increasing ability of Dd2 to invade...

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Identifiers

PMID: 29636510
DOI: 10.1038/s41598-018-24218-0
PMCID: PMC5893586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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