Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level.

Scientific reports - 14 Jan 2020

Nyarko Prince B, Tarr Sarah J, Aniweh Yaw, Stewart Lindsay B, Conway David J, Awandare Gordon A

Abstract excerpt

The central role that erythrocyte invasion plays in Plasmodium falciparum survival and reproduction makes this process an attractive target for therapeutic or vaccine development. However, multiple invasion-related genes with complementary and overlapping functions afford the parasite the plasticity to vary ligands used for invasion, leading to phenotypic variation and immune evasion. Overcoming the challenge...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Erythrocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Phenotype

Share to Plasmodium falciparum

Source

Open in PubMed Open full text

Identifiers

PMID: 31937828
DOI: 10.1038/s41598-019-56386-y
PMCID: PMC6959351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level.PMID 31937828Read ↗

Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture.Semantic proximity Read ↗

Erythrocyte invasion by Plasmodium falciparum: multiple ligand-receptor interactions and phenotypic switching.Semantic proximity Read ↗

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genesSemantic proximity Read ↗

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.Semantic proximity Read ↗

Stochastic Expression of Invasion Genes in Plasmodium falciparum SchizontsSemantic proximity Read ↗

Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular InteractionsSemantic proximity Read ↗

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human ErythrocytesSemantic proximity Read ↗

Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human ErythrocytesSemantic proximity Read ↗

<i>Plasmodium falciparum</i> schizont stage transcriptome variation among clinical isolates and laboratory-adapted clonesSemantic proximity Read ↗

Phenotypic switching and var gene transcription in Plasmodium falciparum.Semantic proximity Read ↗

Epigenetic Silencing of Plasmodium falciparum Genes Linked to Erythrocyte InvasionSemantic proximity Read ↗

Characterisation of the erythrocyte invasion phenotype of FCB-2: A South American P. falciparum reference strain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.