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Article

Profiling and genetic control of the murine immunoglobulin G glycome.

Nature chemical biology - 1 May 2018

Krištić Jasminka, Zaytseva Olga O, Ram Ramesh, Nguyen Quang, Novokmet Mislav, Vučković Frano, Vilaj Marija, Trbojević-Akmačić Irena, Pezer Marija, Davern Kathleen M, Morahan Grant, Lauc Gordan

Abstract excerpt

Immunoglobulin G (IgG) glycosylation is essential for function of the immune system, but the genetic and environmental factors that underlie its inter-individual variability are not well defined. The Collaborative Cross (CC) genetic resource harnesses over 90% of the common genetic variation of the mouse. By analyzing the IgG glycome composition of 95 CC strains, we made several important observations: (i)...

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PMID: 29632412
DOI: 10.1038/s41589-018-0034-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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