Article
Comparative Assessment of Small and Large Intestine Biopsies for Ex Vivo HIV-1 Pathogenesis Studies.
AIDS research and human retroviruses - 1 Oct 2018
Elliott Julie, Fulcher Jennifer A, Ibarrondo F Javier, Tanner Karen, McGowan Ian, Anton Peter A
Abstract excerpt
Ex vivo mucosal explants have become a mainstay of HIV-1 studies using human tissue. In this study, we examine the baseline phenotypic and virologic differences between biopsies derived from the small intestine (SI) and large intestine (LI) for use in ex vivo explant studies. To do this, we collected endoscopic mucosal biopsies from both SI and LI from the same healthy, HIV-seronegative participants. Mucosal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.