Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses

5 Apr 2018

Abstract excerpt

Adeno-associated virus (AAV) penetrates the blood-brain barrier, but it is unknown whether AAV penetrates other tight junctions. Genetic manipulation of testis has been hampered by the basement membrane of seminiferous tubules and the blood-testis barrier (BTB), which forms between Sertoli cells and divides the tubules into basal and adluminal compartments. Here, we demonstrate in vivo genetic manipulation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29628393
DOI: 10.1016/j.stemcr.2018.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated VirusesPMID 29628393Read ↗

Transgenesis and Genome Editing of Mouse Spermatogonial Stem Cells by Lentivirus Pseudotyped with Sendai Virus F Protein.Semantic proximity Read ↗

Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile miceSemantic proximity Read ↗

Germline Stem Cell Transplantation and TransgenesisSemantic proximity Read ↗

Tight junctions in the testis: new perspectivesSemantic proximity Read ↗

Restoration of Spermatogenesis in Infertile Mice by Sertoli Cell Transplantation1Semantic proximity Read ↗

Sertoli cell ablation and replacement of the spermatogonial niche in mouseSemantic proximity Read ↗

Regulation of the Spermatogonial Stem Cell NicheSemantic proximity Read ↗

Successful transplantation of spermatogonial stem cells into the seminiferous tubules of busulfan-treated miceSemantic proximity Read ↗

Homing of Mouse Spermatogonial Stem Cells to Germline Niche Depends on β1-IntegrinSemantic proximity Read ↗

AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failureSemantic proximity Read ↗

Microinjection of antisense oligonucleotides into living mouse testis enables lncRNA function studySemantic proximity Read ↗

Mutational insertion of a ROSA26-EGFP transgene leads to defects in spermiogenesis and male infertility in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.