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Article

Restoration of Spermatogenesis in Infertile Mice by Sertoli Cell Transplantation1

1 Mar 2003

Abstract excerpt

The niche is considered to play an important role in stem cell biology. Sertoli cells are the only somatic cells in the seminiferous tubule that closely interact with germ cells to create a favorable environment for spermatogenesis. However, little is known about how Sertoli cells develop to form the male germ line niche. We report here that Sertoli cells recovered and dissociated from testes of donor male mice...

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PMID: 12604661
DOI: 10.1095/biolreprod.102.009977

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