Article
CYP1A1 gene polymorphisms modify the association between PM10 exposure and lung function.
Chemosphere - 1 Jul 2018
Kim Hyun-Jin, Park Jin-Ho, Seo Yong-Seok, Holsen Thomas M, Hopke Philip K, Sung Joohon, Son Ho-Young, Yun Jae Moon, Kwon Hyuktae, Cho Belong, Kim Jong-Il
Abstract excerpt
Genetic epidemiological studies have provided evidence that several genes modify the link between air pollution and lung function. We assessed whether the adverse impacts of particulate matter with an aerodynamic diameter ≤10 μm (PM10) on lung function are modified by CYP1A1 gene polymorphisms in Korean adults. We used health check-up data from 1817 men, and the annual mean concentrations of ambient PM10...
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