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Mechanisms of Staphylococcus aureus Antibiotics Resistance Revealed by Adaptive Laboratory Evolution.

Current microbiology - 6 Jan 2025

Ma Shiwei, Xu Yufan, Ma Juanjuan, Luo Dan, Huang Zixin, Wang Longlong, Xie Weile, Luo Zhen, Zhang Huanhuan, Jiang Jijie, Jin Yaozhong, Zhang Jianming, Zhu Jianguo, Wang Zhe

Abstract excerpt

Infection caused by drug-resistant Staphylococcus aureus is a serious public health and veterinary concern. Lack of a comprehensive understanding of the mechanisms underlying the emergence of drug-resistant strains, it makes S. aureus one of the most intractable pathogenic bacteria. To identify mutations that confer resistance to anti-S. aureus drugs, we established a laboratory-based adaptive evolution system...

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PMID: 39762552
DOI: 10.1007/s00284-024-03980-7

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