Article
Comparative analysis of long noncoding RNAs in long-lived mammals provides insights into natural cancer-resistance.
RNA biology - 1 Nov 2020
Jiang Jian-Jun, Kong Qing-Peng
Abstract excerpt
Mouse and rats are staple model organisms that have been traditionally used for oncological studies; however, their short lifespan and highly prone to cancers limit their utilizationsin understanding the mechanisms of cancer resistance. In recent years, several studies of the non-standard long-lived mammalian species like naked mole rat (NMR) have provided new insights of mechanisms in natural anti-cancer. How...
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