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Article

SPIONs mediated magnetic actuation promotes nerve regeneration by inducing and maintaining repair-supportive phenotypes in Schwann cells.

Journal of nanobiotechnology - 27 Mar 2022

Liu Ting, Wang Yang, Lu Laijin, Liu Yi

Abstract excerpt

BACKGROUND: Schwann cells, the glial cells in the peripheral nervous system, are highly plastic. In response to nerve injury, Schwann cells are reprogrammed to a series of specialized repair-promoting phenotypes, known as repair Schwann cells, which play a pivotal role in nerve regeneration. However, repair Schwann cells represent a transient and unstable cell state, and these cells progressively lose their...

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Identifiers

PMID: 35351151
DOI: 10.1186/s12951-022-01337-5
PMCID: PMC8966266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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