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Article

miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3

28 Mar 2018

Abstract excerpt

In a previous study, we showed that microRNA-675 (miR-675) was significantly down-regulated in patients with tricho-dento-osseous (TDO) syndrome. One of the main features of TDO syndrome is dentin hypoplasia. Thus, we hypothesize that miR-675 plays a role in dentin development. In this study, we determined the role of miR-675 in the odontogenic differentiation of human dental pulp cells (hDPCs). Stable...

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PMID: 29604248
DOI: 10.1016/j.yexcr.2018.03.035

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