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Article

DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis.

Clinical science (London, England : 1979) - 15 Nov 2017

Zhao Na, Zeng Li, Liu Yang, Han Dong, Liu Haochen, Xu Jian, Jiang Yuxi, Li Cuiying, Cai Tao, Feng Hailan, Wang Yixiang

Abstract excerpt

The underlying molecular mechanism of the increased bone mass phenotype in Tricho-dento-osseous (TDO) syndrome remains largely unknown. Our previous study has shown that the TDO point mutation c.533A>G, Q178R in DLX3 could increase bone density in a TDO patient and transgenic mice partially through delaying senescence in bone marrow mesenchymal stem cells (BMSCs). In the present study, we provided a new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28963438
DOI: 10.1042/CS20171231

Genes

DLX3
NOMO1
CCK

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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