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Article

DLX3 mutation negatively regulates odontogenic differentiation of human dental pulp cells.

Archives of oral biology - 1 May 2017

Zeng Li, Zhao Na, Han Dong, Liu Haochen, Liu Yang, Wang Yixiang, Feng Hailan

Abstract excerpt

OBJECTIVES: The purpose of this study was to investigate the role of a novel mutant DLX3 on the odontogenic differentiation of human dental pulp cells (hDPCs) in tricho-dento-osseous (TDO) syndrome. DESIGN: hDPCs were obtained from the healthy premolars, stably-expressing wild-type DLX3 (WT), novel mutant DLX3 (Mu) and control vector (NC) cells were generated using recombinant lentiviruses. The proliferation...

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Source

Identifiers

PMID: 28135572
DOI: 10.1016/j.archoralbio.2017.01.011

Genes

DLX3
DSPP
DLX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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