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Article

Effect of histone demethylase KDM5A on the odontogenic differentiation of human dental pulp cells

1 Jan 2020

Abstract excerpt

Human dental pulp cells (hDPCs) possess the capacity to differentiate into odontoblast-like cells in response to exogenous stimuli. Histone methylation is one of the most robust epigenetic marks and is essential for the regulation of multiple cellular processes. Previous studies have shown that histone methyltransferases (HMTs) and histone demethylases (HDMs) are crucial for the osteogenic differentiation of...

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PMID: 32208897
DOI: 10.1080/21655979.2020.1743536

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