Article
Solid papillary breast carcinomas resembling the tall cell variant of papillary thyroid neoplasms (solid papillary carcinomas with reverse polarity) harbour recurrent mutations affecting IDH2 and PIK3CA: a validation cohort.
Histopathology - 1 Aug 2018
Lozada John R, Basili Thais, Pareja Fresia, Alemar Barbara, Paula Arnaud Da Cruz, Gularte-Merida Rodrigo, Giri Dilip D, Querzoli Patricia, Cserni Gabor, Rakha Emad A, Foschini Maria P, Reis-Filho Jorge S, Brogi Edi, Weigelt Britta, Geyer Felipe C
Abstract excerpt
AIMS: Solid papillary breast carcinoma resembling the tall cell variant of papillary thyroid neoplasms (BPTC), also known as solid papillary carcinoma with reverse polarity, is a rare histological type of breast cancer that resembles morphologically the tall cell variant of papillary thyroid carcinoma. BPTCs are characterised by IDH2 R172 hotspot somatic mutations or mutually exclusive TET2 somatic mutations,...
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