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An advanced human in vitro co-culture model for translocation studies across the placental barrier

29 Mar 2018

Abstract excerpt

Although various drugs, environmental pollutants and nanoparticles (NP) can cross the human placental barrier and may harm the developing fetus, knowledge on predictive placental transfer rates and the underlying transport pathways is mostly lacking. Current available in vitro placental transfer models are often inappropriate for translocation studies of macromolecules or NPs and do not consider barrier function...

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PMID: 29599470
DOI: 10.1038/s41598-018-23410-6

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