Article

A straightforward cell culture insert model to incorporate biochemical and biophysical stromal properties into transplacental transport studies

2024-04-25

Abstract excerpt

<h4>Introduction</h4> The placental extracellular matrix (ECM) dynamically remodels over pregnancy and in disease. How these changes impact placental barrier function is poorly understood as there are limited in vitro models of the placenta with a modifiable stromal compartment to mechanistically investigate these extracellular factors. We developed a straightforward method to incorporate uniform hydrogels into...

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Identifiers and source

Literature Corpus work: 95dd44b4-753d-54e1-a484-4ae751ba7833
DOI: 10.1101/2024.04.19.590317

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