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Targeted lipid nanoparticles to prevent trans-placental passage in the ex vivo human placental cotyledon perfusion model

14 Oct 2024

Abstract excerpt

Medication use during pregnancy poses risks to both the mother and the fetus. These risks include an elevated potential for fetotoxicity due to placental drug transport. Nanomedicines offer a promising solution by potentially preventing trans-placental passage. Targeted nanomedicines could enhance safety and efficacy in treating maternal or placental pathophysiology. Our study investigates placental transfer...

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PMID: 39402393
DOI: 10.1007/s13346-024-01715-6

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