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Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study.

Nutrients - 28 Mar 2018

Kwan Sze Ting Cecilia, King Julia H, Grenier Jennifer K, Yan Jian, Jiang Xinyin, Roberson Mark S, Caudill Marie A

Abstract excerpt

The placental epigenome regulates processes that affect placental and fetal development, and could be mediating some of the reported effects of maternal choline supplementation (MCS) on placental vascular development and nutrient delivery. As an extension of work previously conducted in pregnant mice, the current study sought to explore the effects of MCS on various epigenetic markers in the placenta. RNA and DNA...

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Identifiers

PMID: 29597262
DOI: 10.3390/nu10040417
PMCID: PMC5946202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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