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Article

Maternal Choline Supplementation Alters Fetal Growth Patterns in a Mouse Model of Placental Insufficiency.

Nutrients - 18 Jul 2017

King Julia H, Kwan Sze Ting Cecilia, Yan Jian, Klatt Kevin C, Jiang Xinyin, Roberson Mark S, Caudill Marie A

Abstract excerpt

Impairments in placental development can adversely affect pregnancy outcomes. The bioactive nutrient choline may mitigate some of these impairments, as suggested by data in humans, animals, and human trophoblasts. Herein, we investigated the effects of maternal choline supplementation (MCS) on parameters of fetal growth in a Dlx3+/- (distal-less homeobox 3) mouse model of placental insufficiency. Dlx3+/- female...

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Identifiers

PMID: 28718809
DOI: 10.3390/nu9070765
PMCID: PMC5537879

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