Article
Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet.
PloS one - 21 Dec 2010
Gallou-Kabani Catherine, Gabory Anne, Tost Jörg, Karimi Mohsen, Mayeur Sylvain, Lesage Jean, Boudadi Elsa, Gross Marie-Sylvie, Taurelle Julien, Vigé Alexandre, Breton Christophe, Reusens Brigitte, Remacle Claude, Vieau Didier, Ekström Tomas J, Jais Jean-Philippe, Junien Claudine
Abstract excerpt
BACKGROUND: Changes in imprinted gene dosage in the placenta may compromise the prenatal control of nutritional resources. Indeed monoallelic behaviour and sensitivity to changes in regional epigenetic state render imprinted genes both vulnerable and adaptable. METHODS AND FINDINGS: We investigat...
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