Article
High mobility group protein HMGB2 is a critical regulator of plasmodium oocyst development.
The Journal of biological chemistry - 20 Jun 2008
Gissot Mathieu, Ting Li-Min, Daly Thomas M, Bergman Lawrence W, Sinnis Photini, Kim Kami
Abstract excerpt
The sexual cycle of Plasmodium is required for transmission of malaria from mosquitoes to mammals, but how parasites induce the expression of genes required for the sexual stages is not known. We disrupted the Plasmodium yoelii gene encoding high mobility group nuclear factor hmgb2, which encodes...
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