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Article

Pioglitazone is effective for multiple phenotyepes of the Zucker fa/fa rat with polycystc ovary morphology and insulin resistance.

Journal of ovarian research - 27 Mar 2018

Morishita Miyuki, Endo Toshiaki, Baba Tsuyoshi, Kuno Yoshika, Ikeda Keiko, Kiya Tamotsu, Honnma Hiroyuki, Saito Tsuyoshi

Abstract excerpt

BACKGROUND: Hyperandrogenism and insulin resistance may be related to the etiology of PCOS. Zucker fa/fa rats with polycystic ovary are obese, have insulin resistance without diabetes mellitus or hyperandrogenism and can be utilized as PCOS model rats without effects of hyperandrogenemia. PCOS patients are reported to have elevated levels of serum anti-Mullerian hormone (AMH), which has an inhibitory action on...

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Identifiers

PMID: 29580285
DOI: 10.1186/s13048-018-0395-y
PMCID: PMC5870225

Genes

AMH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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