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Article

Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.

Biology of reproduction - 11 Apr 2023

Liu Shihe, Yao Qiyang, Li Xiaolian, Wu Haowen, Sun Changwei, Bai Wenpei, Kang Jihong

Abstract excerpt

Polycystic ovary syndrome (PCOS) is one of the most common female reproductive and metabolic disorders. The ketogenic diet (KD) is a diet high in fat and low in carbohydrate. The beneficial effects of KD intervention have been demonstrated in obese women with PCOS. The underlying mechanisms, however, remain unknown. The aim of the present study was to investigate the effects of a KD on both reproductive and...

Topics

Humans
Mice
Female
Animals
Polycystic Ovary Syndrome
Diet, Ketogenic
Mice, Inbred C57BL
Phenotype
Inflammation
Dehydroepiandrosterone
Ketones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Disease Models, Animal

Source

Identifiers

PMID: 36688496
DOI: 10.1093/biolre/ioad004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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