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Article

The Genetic Landscape of Hypoplastic Left Heart Syndrome.

Pediatric cardiology - 1 Aug 2018

Yagi Hisato, Liu Xiaoqin, Gabriel George C, Wu Yijen, Peterson Kevin, Murray Stephen A, Aronow Bruce J, Martin Lisa J, Benson D Woodrow, Lo Cecilia W

Abstract excerpt

Hypoplastic left heart syndrome (HLHS) is one of the most lethal congenital heart defects, and remains clinically challenging. While surgical palliation allows most HLHS patients to survive their critical heart disease with a single-ventricle physiology, many will suffer heart failure, requiring heart transplantation as the only therapeutic course. Current paradigm suggests HLHS is largely of hemodynamic origin,...

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Identifiers

PMID: 29569026
DOI: 10.1007/s00246-018-1861-4
PMCID: PMC8565805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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