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Article

Hypoplastic Left Heart Syndrome: Signaling & Molecular Perspectives, and the Road Ahead.

International journal of molecular sciences - 17 Oct 2023

Datta Sayantap, Cao Wangjia, Skillman Mikayla, Wu Mingfu

Abstract excerpt

Hypoplastic left heart syndrome (HLHS) is a lethal congenital heart disease (CHD) affecting 8-25 per 100,000 neonates globally. Clinical interventions, primarily surgical, have improved the life expectancy of the affected subjects substantially over the years. However, the etiological basis of HLHS remains fundamentally unclear to this day. Based upon the existing paradigm of studies, HLHS exhibits a...

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Identifiers

PMID: 37894928
DOI: 10.3390/ijms242015249
PMCID: PMC10607600

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