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Article

MicroRNA-590 is an EMT-suppressive microRNA involved in the TGFβ signaling pathway

25 Sept 2015

Abstract excerpt

Over the last few decades, the epithelial-to-mesenchymal transition (EMT) has been identified as being involved in a number of aspects of physiological processes and various pathological events, including embryonic development and renal fibrosis. Transforming growth factor‑β receptor 2 (TGFβR2) is a widely studied gene, which fulfils a vital role in the TGFβ signaling pathway and exerts a crucial function in the...

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PMID: 26459119
DOI: 10.3892/mmr.2015.4374

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