Article
Next-generation sequencing analysis of a cluster of hepatitis C virus infections in a haematology and oncology center.
PloS one - 1 Jan 2018
Caraballo Cortes Kamila, Rosińska Magdalena, Janiak Maciej, Stępień Małgorzata, Zagordi Osvaldo, Perlejewski Karol, Osuch Sylwia, Pawełczyk Agnieszka, Bukowska-Ośko Iwona, Płoski Rafał, Grabarczyk Piotr, Laskus Tomasz, Radkowski Marek
Abstract excerpt
Molecular characterization of early hepatitis C virus (HCV) infection remains rare. Ten out of 78 patients of a hematology/oncology center were found to be HCV RNA positive two to four months after hospitalization. Only two of the ten patients were anti-HCV positive. HCV hypervariable region 1 (HVR1) was amplified in seven patients (including one anti-HCV positive) and analyzed by next generation sequencing...
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