Article
Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer.
Oncology reports - 1 May 2018
Wang Yipeng, Guo Liping, Feng Lin, Zhang Wen, Xiao Ting, Di Xuebing, Chen Guoji, Zhang Kaitai
Abstract excerpt
Circulating tumour cell (CTC) behaviours are distinct from those of bulk tissues. Thus, treatments to eliminate CTCs differ from the regimens followed to reduce the primary tumour and its metastases. Accordingly, comprehensively deciphering the single nucleotide variant (SNV) profiles in CTCs, which partially determine CTC behaviours, is a priority. Using viable CTCs isolated with the oHSV1‑hTERT‑GFP virus...
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