Article
Molecular interplay between mutant p53 proteins and autophagy in cancer cells.
Biochimica et biophysica acta. Reviews on cancer - 1 Jan 2017
Cordani Marco, Butera Giovanna, Pacchiana Raffaella, Donadelli Massimo
Abstract excerpt
An increasing number of studies highlight the role of mutant p53 proteins in cancer cell growth and in the worsening of cancer patients' clinical outcome. Autophagy has been widely recognized as a main biological event involved in both the regulation of cancer cell proliferation and in the response of several anticancer drugs. A thorough analysis of scientific literature underlines the reciprocal interplay...
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